Zuprevo 18% (Tildipirosin)

$360.00$966.00

 

 

Multi dose vial 

Sterial
Each ml of Zuprevo Injection contains 180 mg tildipirosin.
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Description

Zuprevo 18% is an antimicrobial injectable solution for cattle indicated for the treatment of bovine respiratory disease (BRD) associated with Mannheimia haemolytica, Pasteurella multocida, and Histophilus somni, and for control of respiratory disease in cattle at high risk of developing BRD associated with M. haemolytica, P. multocida and H. somni. For use in beef and non-lactating dairy cattle.

Each ml of Zuprevo contains 180 mg tildipirosin.
A single dose of Zuprevo concentrates in the lungs for 28 days and in bronchial fluid for 21 days to treat and control BRD.
Administer one dose, 1 ml per 100 lbs.
SQ in the neck, not to exceed 10 ml per injection site. Zuprevo is not for use in female dairy cattle 20 months of age or older, or in calves to be processed for veal. 180 mg/ml Tildipirosin.

 

CHEMICAL NOMENCLATURE AND STRUCTURE:

Tildipirosin is the nonproprietary name for (11E,13E)-(4R,5S,6S,7R,9R,15R,16R)-6-(4-Dimethylamino-3,5-dihydroxy-6-methyl-tetrahydro-pyran-2-yloxy)-16-ethyl-4-hydroxy-5,9,13-trimethyl-7-(2-piperidin-1-yl-ethyl)-15-piperidin-1-ylmethyl-oxacyclohexadeca-11,13-diene-2,10-dione. The empirical formula is C41H71N3O8. The chemical structure of tildipirosin is shown below.

 

INDICATIONS:

Zuprevo 18% is indicated for the treatment of bovine respiratory disease (BRD) associated with Mannheimia haemolytica, Pasteurella multocida, and Histophilus somni in beef and non-lactating dairy cattle, and for the control of respiratory disease in beef and non-lactating dairy cattle at high risk of developing BRD associated with Mannheimia haemolytica, Pasteurella multocida, and Histophilus somni.

 

DOSAGE AND ADMINISTRATION:

Inject subcutaneously as a single dose in the neck at a dosage of 4 mg/kg (1 mL/100 lb) body weight (BW). Do not inject more than 10 mL per injection site. Do not puncture the stopper of the respective vial size more than the tested number of punctures, shown in Table 1.

Clinical field studies indicate that administration of Zuprevo 18% (tildipirosin) Injectable Solution is effective for the control of respiratory disease in beef and non-lactating dairy cattle at “high risk” of developing BRD. Calves at high risk of developing BRD typically experience one or more of the following risk factors:

• Commingling from multiple sale barns/sources

• Extended transport times and shrink

• Exposure to wet or cold weather conditions or wide temperature swings

• Stressful arrival processing procedures (such as castration, dehorning, or branding)

• Recent weaning and poor vaccination history

Table 1 Number of punctures tested in the in-use study for the respective vial sizes

Vial size [mL]

Number of punctures tested in the in-use study

50

8

100

8

250

16

WARNINGS:

FOR USE IN ANIMALS ONLY. NOT FOR HUMAN USE. KEEP OUT OF REACH OF CHILDREN.

TO AVOID ACCIDENTAL INJECTION, DO NOT USE IN AUTOMATICALLY POWERED SYRINGES WHICH HAVE NO ADDITIONAL PROTECTION SYSTEM. IN CASE OF HUMAN INJECTION, SEEK MEDICAL ADVICE IMMEDIATELY AND SHOW THE PACKAGE INSERT OR LABEL TO THE PHYSICIAN.

Avoid direct contact with skin and eyes. If accidental eye exposure occurs, rinse eyes with clean water. If accidental skin exposure occurs, wash the skin immediately with soap and water. Tildipirosin may cause sensitization by skin contact.

For technical assistance or to report a suspected adverse reaction, call: 1-800-219-9286.

For customer service or to request a Material Safety Data Sheet (MSDS), call: 1-800-211-3573.

 

 

Remains syringeable in cold weather.

Additional information

Size

100ml, 250ml